Relating to halogenated hydrocarbons

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Carcinogenicity studies on halogenated hydrocarbons.

A series of halogenated compounds was tested by oral intubation in 200 Osborne-Mendel rats and 200 B6C3F1 mice of both sexes. Carbon tetrachloride, used as a positive control, induced liver and adrenal tumors in mice and neoplastic nodules in the livers of rats. 1,2-Dibromoethane and 1,2-dibromo-3-chloropropane caused stomach tumors with many metastases in both rats and mice. Chloroform, known ...

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ژورنال

عنوان ژورنال: Nature

سال: 1982

ISSN: 0028-0836,1476-4687

DOI: 10.1038/296688a0